Detalhe da pesquisa
1.
The crystal structure of Mycobacterium thermoresistibile MurE ligase reveals the binding mode of the substrate m-diaminopimelate.
J Struct Biol
; 215(2): 107957, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36944394
2.
Mutations and insights into the molecular mechanisms of resistance of Mycobacterium tuberculosis to first-line.
Genet Mol Biol
; 46(1 Suppl 2): e20220261, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36718771
3.
Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors.
Bioorg Med Chem
; 28(15): 115600, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32631571
4.
Crystal structure of dihydrofolate reductase from the emerging pathogenic fungus Candida auris.
Acta Crystallogr D Struct Biol
; 79(Pt 8): 735-745, 2023 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37428844
5.
An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity.
Acta Crystallogr D Struct Biol
; 76(Pt 9): 868-875, 2020 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32876062
6.
Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase.
PLoS Negl Trop Dis
; 14(10): e0008091, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33017394
7.
Structural Basis for the Interaction and Processing of ß-Lactam Antibiotics by l,d-Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis.
ACS Infect Dis
; 5(2): 260-271, 2019 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30556998
8.
Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin.
ACS Chem Biol
; 14(5): 925-933, 2019 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-30995396
9.
Crystal structures of the closed form of Mycobacterium tuberculosis dihydrofolate reductase in complex with dihydrofolate and antifolates.
Acta Crystallogr D Struct Biol
; 75(Pt 7): 682-693, 2019 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31282477
10.
Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase from Mycobacterium tuberculosis.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 63(Pt 1): 1-6, 2007 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17183161
11.
Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.
ACS Chem Biol
; 12(11): 2779-2787, 2017 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28876898
12.
Molecular models of tryptophan synthase from mycobacterium tuberculosis complexed with inhibitors.
Cell Biochem Biophys
; 44(3): 375-84, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16679524
13.
Mycobacterium tuberculosis dihydrofolate reductase reveals two conformational states and a possible low affinity mechanism to antifolate drugs.
Structure
; 22(1): 94-103, 2014 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24210757
14.
Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis.
J Struct Biol
; 159(3): 369-80, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17588773
15.
Crystal structure of human PNP complexed with hypoxanthine and sulfate ion.
Biochem Biophys Res Commun
; 326(2): 335-8, 2005 Jan 14.
Artigo
Inglês
| MEDLINE | ID: mdl-15582582
16.
Structural basis for inhibition of human PNP by immucillin-H.
Biochem Biophys Res Commun
; 309(4): 917-22, 2003 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-13679061
17.
Interaction of shikimic acid with shikimate kinase.
Biochem Biophys Res Commun
; 325(1): 10-7, 2004 Dec 03.
Artigo
Inglês
| MEDLINE | ID: mdl-15522194